To Puff or Definitely not to Puff

Take a drag of that cigarette (not!). Here's what will happen if you do (so don't!)...

1. Hyperglycemia. Your biochemical insulin production completely shuts down so your glucose blood level balance gets out of rhythm Glucose levels rise. You become temporarily hyperglycemic.
2. Dopamine Incease. Neurosynaptic re-uptake transporters for dopamine become blocked so the amount of dopamine in the synapses keeps flowing and the recieving cell continues recieving the neurotransmitters. Dopamine pleasure circuits keep firing, but become "abused" and will be more difficult to fire in the future.
3. Epinephrine Release. Your brain's hormonal centers start a sequence that releases epinephrine. You feel temporarily more alert, but later, your flight/fight response will be thrown out of whack by this repetitive "false alarm".

Those happen with every drag -- a drag, yeah...that's right!

This of course doesn't mention the long-term build-up. The emphyzema, angina pectoris (chest pain due to lack of blood to the heart, or ischemia), chronic bronchitis, system fibrosis (lung tissuue scarring), throat, gum, and lung cancer. Yeah, not fun!